Most interestingly, global efficiency of networks in patients was increased compared to controls whereas modularity was not altered.
In particular, the interaction between attention network and default mode network was comparable between the group after hemispherectomy and a healthy control group. The impressive result was that the interhemispheric connectivity in brains with only one hemisphere is strikingly similar to the functional network organization in brains with two hemispheres. Investigation of these chronic cases has revealed important insights into long-term adaptation of brain networks to hemispherectomy. The authors examined a sample of six high functioning individuals at the age of 20–31 years, who underwent anatomical hemispherectomy between birth and the age of 10. What happens to brain networks after removal of a cerebral hemisphere? This question was addressed in a recently published fMRI study by Kliemann and colleagues ( 1). Intrinsic functional connectivity of the brain in adults with a single cerebral hemisphere. The article did not undergo external peer review.Ĭomment on: Kliemann D, Adolphs R, Tyszka JM, Fischl B, Yeo BTT, Nair R, Dubois J, Paul LK. Email: and Peer Review: This article was commissioned by the Editorial Office, Quantitative Imaging in Medicine and Surgery. Franz Tappeiner Hospital, Merano, Italy Spinal Cord Injury and Tissue Regeneration Center Salzburg, Salzburg, Austria Department of Neurology, Paracelsus Medical University Salzburg, Salzburg, Austria.
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